I don't watch the 2016 reboot so I'm worried to know what "has a more...supportive relationship with his cousin gwen" means. Especially considering that the original series was bad enough in that department (though at least it could be chalked up to not originally being related when the show was in development). The reboot would have no excuse.
but the stories weave pretty well together. Granted, we could have gotten more hints of what Granny did in her past(unless I missed something in that moment she berated the pokemon to get out)