Hoshino's debut manga Continue appeared in the Weekly Shonen Jump in 2003. She also wrote an unpublished manga called Book-man. Many of her characters come from earlier works such as these while some are modeled after real people such as famous scientist sand, in one case, a silver accessory brand name. She is the author of the manga pilot Zone, which was published in Shueisha's magazine Akamaru Jump. This later paved the way for the D.Gray-man series, which began in 2004 and is currently serialized in Weekly Shonen Jump. An anime, as well as two novels, have been adapted from the series. The manga is being sold in ten countries, including the United States, Germany, and France. An English dub of the anime is expected in early 2009 from FUNimation.
In Japan, D.Gray-man was put on a hiatus due to Hoshino falling seriously ill and once again because of an unspecified injury. However the series continued shortly after.
Hoshino also has a cat named Koro, often translated as Coro, who has a birth defect and has difficulty walking. Even so, she says that Koro does its best to move around, often rolling around on the floor. According to Hoshino, this cheers her up, especially when her editor, Yoshida, yells at her. In her opinion, Koro resembles Timcanpy.
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