Toy Story 3, at the end when Andy gives away the toys.
Half of Up.
Lion King, when Mufassa died.
HP and the Deathly Hallows when Dobby/Lupin/Tonks/Fred/Harry die, and the epilogue really gets me.
HP and the Order of the Phoenix, when Sirius dies.
HP and the Half-Blood Prince when Dumbledore dies.
Armageddon, when the father sacrifices himself to save the world and he's saying goodbye to his daughter.
Half of Up.
Lion King, when Mufassa died.
HP and the Deathly Hallows when Dobby/Lupin/Tonks/Fred/Harry die, and the epilogue really gets me.
HP and the Order of the Phoenix, when Sirius dies.
HP and the Half-Blood Prince when Dumbledore dies.
Armageddon, when the father sacrifices himself to save the world and he's saying goodbye to his daughter.