We really need something to look forward to in 2023. The 2022 lineup, especially for the second half of the year, has been mainly niche IPs that the majority of Nintendo fans don't care about, we need to start seeing some news for some bigger IPs. Zelda and Metroid ports would be okay, but we could really use an announcement for a Spring game. Like DK. Whatever happened to that? The rumors were flying around about a DK game last year for the 40th anniversary, to the point where there's too much smoke for there to be no fire, and then... crickets. Where is that game?
Also, we need to hear SOMETHING about BotW2. Either announce another delay or lift the lid on WTF the game actually is. This game is too high profile for us to know this little this close to release, if it really is on target for a Spring 2023 release it's high time we actually learn something about it if they want it to sell gangbusters like the first game.
As for Prime 4, I doubt they announce it now. Especially not after they announced it too early to begin with. I'm guessing we don't see it again until E3 2023, that feels like the right time and place for that kind of announcement. Feeling the same about Odyssey 2 for that matter, that's another IP we really need to see soon, but a flagship game like that is probably not going to be announced in a September Direct (at best we'll get a quick teaser, but we tend not to get those for Mario games).