Heh, I was getting ready to post a question about Ash's possible father until I saw this thread.
I was watching Pokemon Chronicles today and it seems that Silver might be Ash's dad. When Richie mentioned "Ash", Silver seemed pretty shocked. Richie was saying how Ash is just as stubborn as he (Richie) is, and Silver said that Richie reminded him of himself for that same reason (well, not so much "stubborn", but determined). If Richie reminds Silver of himself as a younger person, and Ash reminds Richie of himself, then that would be a connection? Also, Silver has a similar appearance to Ash (his lead Pokemon on his shoulder, thick eyebrows, bangs, etc.). So umm yeah...
Oh, and I think Agatha might be Gary's grandmother, because she mentions how Professor Oak used to be a handsome young man or something like that in the game. But that's the only evidence (if it should even be considered evidence) I have.